AI is particularly useful in neuroscience because data-driven AI models can analyse complex datasets to help researchers and health practitioners in diagnosing, treating and preventing brain diseases. As we speak, researchers are working on developing health data platforms and AI models to predict whether a person is likely to develop dementia. This enables early treatment, which is crucial in case of neurodegenerative diseases. However, these groundbreaking technologies come with several legal and ethical dilemmas. The AI models train on large amounts of data, including sensitive personal data relating to health. In the case of dementia research, it remains essential to process data of vulnerable groups – persons with dementia. The purpose of this panel is to explore the legal, ethical and technical considerations of such research, in the context of the applicable EU legal framework (GDPR, AIA, DA, EHDS, MDR).